In a training, RiskGONE brings a simple and efficient guidance on how to determine the effective density of engineered nanomaterials – ENMs using volumetric centrifugation method (VCM). In cellular assays, ENMs can form agglomerates in presence of cell culture media which change the size and the effective density of nanoparticles. This agglomeration can impact the…

Finished in 2021, PATROLS was an international project combining a team of academics, industrial scientists, government officials and risk assessors to deliver advanced and realistic tools and methods for nanomaterial safety assessment. PATROLS achieved significant results over its lifetime and left a substantial legacy which can be used by industry, regulators and researchers to help move towards…

A new RiskGone training material provides guidance on how to develop appropriate scientifically validated Nano-(Q)SAR/(Q)SPR models for the development of safe-by-design nanomaterials as well as regulatory purposes. Nano-(Q)SAR/(Q)SPR models are an adaptation of (Q)SAR/(Q)SPR methodology for nanomaterials, where the models may be applied for nanoforms of the same substance or nanoforms of different substances. The…

In a new training material for RiskGone, a neural network provides an overview of QSAR models and how they can be used. QSAR models define the relationship between the variance in molecular structures and the variance in a modelled biological activity for a group of sufficiently similar compounds. Models can be used to obtain missing data…

Making the gel drops: cells embedded in agarose are put on slides Dates: 15th-19th March 2021 Location: remote/virtual The Norwegian Institute for Air Research (NILU), coordinator of RiskGONE, is providing a practical online course/video learning on the Comet assay. This training workshop represents the second edition of a series of trainings to be organised as part…